Scientific & Medical Presentations

Date Title
October 19, 2024
2024 AAO: Eichenbaum D, et al. 52-week Sustained Efficacy and Treatment Burden Reduction with OTX-TKI in the US Phase 1 Trial for nAMD
September 16, 2024
2024 Retina Society Late Breaker: Marcus D, et al. Safety and Efficacy of OTX-TKI in Moderately Severe to Severe NPDR: One Year Results from the HELIOS Phase 1 Trial
July 18, 2024
2024 ASRS Late Breaker: Dhoot D et al. Interim Safety and Efficacy Results from the Phase 1 HELIOS Trial of Sustained-Release Axitinib Implant (OTX-TKI) for NPDR
June 8, 2024
2024 CTS: Dhoot D. Learnings from the Phase 1 AXPAXLI HELIOS Diabetic Retinopathy Study
May 9, 2024
2024 ARVO: Blizzard C, et al. Pharmacodynamic efficacy of second-generation intravitreal axitinib implant (Axpaxli) in a VEGF challenge rabbit model
May 6, 2024
2024 ARVO: Patil M, et al. Optimized pharmacokinetic profile of intravitreal axitinib intravitreal implant (Axpaxli): a comparison of first- and second-generation implants
May 6, 2024
2024 ARVO: Patil M, et al. Long-term safety of repeated intravitreal axitinib implant (Axpaxli) administrations in non-human primates
April 6, 2024
2024 ASCRS, Gallardo M et al. Travoprost Intracameral Implant (OTX-TIC) for Open-angle Glaucoma or Ocular Hypertension: Results from a Phase 2 Clinical Trial
November 3, 2023
2023 AAO, Xu B et al. Real-world Safety Analysis of 50,000 Patients Treated with Intracanalicular Dexamethasone Insert Using IRIS® Registry
November 3, 2023
2023 AAO, Bovelle R et al. Real-World Characteristics of 50,000 Patients Treated With Intracanalicular Dexamethasone Insert: Analysis using IRIS® Registry
October 13, 2023
2023 The Retina Society, Avery R. OTX-TKI, Sustained-Release Axitinib Hydrogel Implant, for Neovascular Age-Related Macular Degeneration
June 10, 2023
2023 CTS, Khanani A. 12-Month Update on Randomized, Controlled, Trial of OTX-TKI (Axitinib Intravitreal Implant) for the Treatment of Wet AMD
May 7, 2023
2023 ASCRS, Spencer P et al. Safety and Effectiveness Comparison of Hydrogel-Based Intracanalicular Dexamethasone Insert Placement in the Lower Versus Upper Punctum: The SPENCER Study
May 7, 2023
2023 ASCRS, Nijm L et al. Thermal Pulsation Therapy with Dextenza Versus Prednisolone Acetate or Sham for Meibomian Gland Dysfunction with Inflammation
May 7, 2023
2023 ASCRS, Early A, et al. Prospective Evaluation of Eye Drop Self-Administration Accuracy in a Real-World Patient Population
May 7, 2023
2023 ARVO, Stoutin J et al. Presence of Medical Conditions that Can Impair Patients with Glaucoma from Administering Topical Glaucoma Medications – A Study Using the Sight Outcomes Research Collaborative (SOURCE) Repository
May 7, 2023
2023 ARVO, Stoutin J et al. Presence of Medical Conditions that Can Impair Patients with Glaucoma from Administering Topical Glaucoma Medications – A Study Using the Sight Outcomes Research Collaborative (SOURCE) Repository
April 26, 2023
2023 ARVO, Patel C et al. Preclinical Safety and Tolerability of Repeated Intracameral Travoprost Implant (OTX-TIC) Administrations
April 26, 2023
2023 ARVO, Pehlivaner M et al. Controlled Release of Adeno-Associated Viruses (AAVs) Using Hydrogel Implants Improve GFP Expression and Reduce Anti-Drug Antibody (ADA) Titers and Inflammation in Rabbits
April 23, 2023
2023 ARVO, Moshfeghi A et al. U.S. Phase 1 Study of Intravitreal Axitinib Implant (OTX-TKI) for Neovascular Age-related Macular Degeneration
February 11, 2023
2023 Angiogenesis, Exudation and Degeneration, Moshfeghi A et al. Update on a Hydrogel-Based Intravitreal Axitinib Intravitreal Implant (OTX-TKI) for the Treatment of Neovascular AMD
September 30, 2022
2022 AAO Retina Subspeciality Day, Dhoot D et al: Interim Safety and Efficacy Data from a Phase 1 Clinical Trial of Sustained-release Axitinib Hydrogel Implant (OTX-TKI) in Wet AMD Subjects: 7-month Analysis
September 30, 2022
2022 AAO eposter, Moshfeghi A et al, Australia-based Phase 1 Trial of a Novel, Hydrogel-based, Intravitreal Axitinib Implant for the Treatment of Neovascular Age-related Macular Degeneration
May 19, 2022
2022 ASGCT eposter, Lu S et al, Development of Hydrogel Implants for the Sustained Delivery of Adeno-Associated Viruses in Ocular Gene Therapy
May 19, 2022
2022 ASGCT, Pehlivaner M et al, Reduced Ocular Inflammation and Improved GFP Expression in Rabbits with Controlled Release of Adeno-Associated Virus from Degradable Hydrogel Implants
May 3, 2022
2022 ARVO, Nijm L et al. Efficacy and Safety of OTX-DED Dexamethasone Intracanalicular Insert in Subjects with Dry Eye Disease: A Multicenter, Randomized, Vehicle-Controlled Phase 2 Study
May 3, 2022
2022 ARVO, Kahn E et al. A Pharmacokinetic and Tolerability Study of a Novel Hydrogel-based Axitinib Intravitreal Implant (OTX-TKI) in Non-Human Primates
May 3, 2022
2022 ARVO, Patel C et al. A 6-Month GLP Toxicology Study of a Novel Hydrogel-based, Axitinib Intravitreal Implant (OTX-TKI) in Non-Human Primates
May 3, 2022
2022 ARVO, Blizzard C et al. Safety and Pharmacodynamic Assessment of Repeated Intracameral Travoprost Implant Administration in Beagle Dogs
May 3, 2022
2022 ARVO, Priem M et al. Pharmacokinetics of a Hydrogel-based Besifloxacin Intracanalicular Insert in Canines
May 3, 2022
2022 ARVO, Uzun O et al. Pharmacokinetics of a Hydrogel-based Nepafenac Intracanalicular Insert in Canines
April 25, 2022
2022 ASCRS, Mbagwu M et al. Real-World Characteristics of Patients Treated with Intracanalicular Dexamethasone Insert: An IRIS Registry Analysis 2019-2021
April 25, 2022
2022 ASCRS, Chang RT et al. Real-World Safety Analysis of an Intracanalicular Dexamethasone Insert Using the Intelligent Research in Site (IRIS) Registry
April 25, 2022
2022 ASCRS, Silverstein SM et al. Effects of Punctal Occlusion on Ocular Itching and Conjunctival Redness in Subjects with Allergic Conjunctivitis
April 25, 2022
2022 ASCRS, Silverstein SM et al. Sustained 30 Day Effect of an Intracanalicular Dexamethasone Insert for Treating Ocular Itching Associated with Allergic Conjunctivitis
April 25, 2022
2022 ASCRS, Christie WC et al. Real-World Allergic Conjunctivitis Treatment Patterns of Eye Care Providers
April 25, 2022
2022 ASCRS, Venkateswaran N et al. Patient Journey for Allergic Conjunctivitis and Initial Management
April 25, 2022
2022 ASCRS, Nijm LM et al. Safety and Efficacy of OTX-DED, an Intracanalicular Dexamethasone Insert, for the Treatment of Episodic Dry Eye Disease: A Phase 2 Study
February 11, 2022
2022 Angiogenesis, Exudation, and Degeneration, Moshfeghi A et al, Update on OTX-TKI Clinical Trials for Macular Disease
February 11, 2022
2022 Glaucoma 360 New Horizons Forum, Goldstein MH et al, OTX-TIC, An Intracameral Hydrogel-based Travoprost Implant to Treat Patients with Glaucoma and Ocular Hypertension
November 12, 2021
2021 AAO, Nijm L et al. Real-World Evidence of an Intracanalicular Dexamethasone Insert Saving Time on Patient Education and Calls for Post-Cataract Surgery Care
November 12, 2021
2021 AAO, Silverstein S et al. Efficacy and Safety of an Intracanalicular Dexamethasone Insert (0.4 mg) for the Treatment of Allergic Conjunctivitis
November 12, 2021
2021 AAO, Goldstein MD et al. A Contemporary Retrospective Analysis of Endophthalmitis Following Cataract Surgery Using the IRIS Registry
November 12, 2021
2021 AAO, Christie W et al. Phase 1/2 Trial Evaluating a Novel, Hydrogel-based Cyclosporine Intracanalicular Insert in Subjects with Dry Eye Disease
November 12, 2021
2021 AAO, Goldberg D et al. Hydrogel-based, Sustained-release Intracameral Travoprost Implant for Glaucoma Therapy: A Phase 1 Clinical Trial
November 12, 2021
2021 AAO, Moshfeghi A et al. Phase 1 Trial of a Novel, Hydrogel-based, Intravitreal Axitinib Implant for the Treatment of Neovascular Age-related Macular Degeneration
November 5, 2021
2021 AAOPT, Whitley W et al. Pooled Analysis Evaluating Efficacy and Safety of an Intracanalicular Dexamethasone Insert for the Treatment of Allergic Conjunctivitis
November 5, 2021
2021 AAOPT, Blender N et al. Effects of Punctal Occlusion on Ocular Itching and Conjunctival Redness Associated with Allergic Conjunctivitis
July 24, 2021
2021 ASCRS, Stephens JD et al. Real World Early Physician Experience Using an Intracanalicular Dexamethasone Insert to Treat Post-Operative Ocular Inflammation and Pain
July 24, 2021
2021 ASCRS, Matossian C et al. Real World Time Savings on Patient Education and Call Backs Related to Post Cataract Therapy Using an Intracanalicular Dexamethasone Insert
July 24, 2021
2021 ASCRS, Nijm L et al. Physician Impressions on Real World Use of Topical Corticosteroids for the Treatment of Allergic Conjunctivitis: Need for a Safer Steroid
July 24, 2021
2021 ASCRS, Rubin JM et al. Pooled Analysis Evaluating Efficacy and Safety of an Intracanalicular Dexamethasone Insert for the Treatment of Allergic Conjunctivitis
July 24, 2021
2021 ASCRS, Shettle L et al. Safety and Efficacy of a Novel Hydrogel-based Cyclosporine Intracanalicular Insert for the Treatment of Dry Eye Disease: A Phase 1 Study
July 24, 2021
2021 ASCRS, Walters TR et al. Evaluating Safety, Tolerability and Efficacy of a Hydrogel-based Intracameral Travoprost Implant in Glaucoma Patients
July 24, 2021
2021 ASCRS, Herndon LW et al. Retrospective Study Comparing the Incidence of Endophthalmitis Following Cataract Surgery in Practices With Access to Hydrogel Sealant
July 24, 2021
2021 ASCRS, Goldstein MH et al. Incidence of Endophthalmitis Following Cataract Surgery and Risk Factors: Retrospective Study Using the IRIS Registry
May 7, 2021
2021 ARVO, Wong J. Phase 1 Study of an Intravitreal Axitinib Hydrogel-based Implant (OTX-TKI) for the Treatment of Neovascular Age-Related Macular Degeneration (nAMD)
May 7, 2021
2021 ARVO, Blizzard C. Ocular Pharmacokinetics of OTX-DED, a Sustained-release Intracanalicular Insert Delivering Dexamethasone, in a Canine Model
May 7, 2021
2021 ARVO, Meyer J. Safety of an Intracanalicular Dexamethasone Insert (DEXTENZA) for the Treatment of Allergic Conjunctivitis: Pooled Post-hoc Analysis of Four Studies
May 7, 2021
2021 ARVO, Goldberg D. Phase 1 Study of an Intracameral Travoprost Hydrogel-based Implant (OTX-TIC) for the Treatment of POAG and Ocular Hypertension
May 7, 2021
2021 ARVO, Vanslette A. Pharmacokinetics of OTX-CSI, a Cyclosporine Intracanalicular Insert, in Surgically Induced Dry Eye Beagle Dogs
May 7, 2021
2021 ARVO, Goldstein MH. Incidence of Endophthalmitis Following Routine or Complex Cataract Surgery in Practices With and Without Access to Hydrogel Sealant: Retrospective Study Using the IRIS Registry
July 16, 2020
Ophthalmic Innovation Summit (Public Company Showcase)

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